Chronic Lymphatic Leukaemia in Man of 84

Hypercalcaemia in chronic lymphatic leukaemia.

A 75 year old woman with a 13 year history of classical chronic lymphatic leukaemia (CLL) developed hypercalcaemia. Unlike previous reports, this was not associated with blastic transformation, hyperparathyroidism or features of multiple myeloma, but was due to classical CLL per se.

Haptoglobins in chronic lymphatic leukaemia.

Haptoglobin phenotypes have been determined in 30 chronic lymphatic leukaemia patients and concentrations determined in 21 of these. The number ofHpl phenotypes is slightly raised but not significantly so compared with a control population and is the same as that in first-degree relatives. Haptoglobin concentrations show higher concentrations in Hpl than Hp2, as has previously been reported. It...

Fragility of leucocytes in chronic lymphatic leukaemia.

Sir, The occurrence of a grossly incorrect result for the 'total leucocyte count' was observed in a case of chronic lymphatic leukaemia when this figure was estimated using the Coulter counter model A with the 'saponin' method of lysing the red cells. In this particular case, the total leucocyte count was estimated in two ways: (a) by taking blood samples in duplicate for the Coulter instrument...

Hepatobiliary candidiasis in chronic lymphatic leukaemia.

Prostatic infiltration in chronic lymphatic leukaemia.

Forty six men with chronic lymphatic leukaemia (CLL) were studied for up to seven years. Six patients required surgery for prostatic outlet obstruction. Histological examination of the prostatic chippings showed variable degrees of infiltration with small mature lymphocytes in all six patients, suggestive of a leukaemic origin for the cells. Patients with chronic lymphatic leukaemia who undergo...